Action on Smoking and Health
America's FIRST Antismoking Organization - Why Join NOW
Everything About Smoking and Health and Nonsmokers' Rights

Action on Smoking and Health

A National Legal-Action Antismoking Organization

Entirely Supported by Tax-Deductible Contributions

Learn How You Can Protect Yourself and Your Loved Ones
From the Deadly Dangers of Even Small Amounts of Smoke
 Home  Search  About ASH  Why Join  Comment  Email Page Contact
Contribute
Custody
Apartments

Maternal and Personal Cigarette Smoking Synergize to Increase Airflow Limitation in Adults

American Journal of Respiratory and Critical Care Medicine, February 15, 2004

By: Mark N. Upton , George Davey Smith , Alex McConnachie , Carole L. Hart and Graham C. M. Watt


Abstract

Susceptibility of the lungs to cigarette smoke is poorly understood. It is not known whether maternal smoking increases chronic obstructive pulmonary disease (COPD) risk. In 1998 we reported an inverse association between maternal smoking (prerecorded) and FEV 1 in adults. Because FEV 1 and FVC are strongly correlated, it is unclear whether the association in question reflects a link with lung volume, airflow limitation, or both. We extended our original analysis to investigate whether maternal and personal smoking synergize to increase airflow limitation. We estimated residual FEV 1 to express FEV 1 variation that was not associated with FVC. Maternal smoking was inversely associated with FVC and FEV 1 irrespective of personal smoking. It was inversely associated with FEV 1 /FVC, forced midexpiratory flow rates (FEF 25–75 [mean forced expiratory flow during the middle half of the FVC], FEF 25–75 /FVC), and residual FEV 1 in current smokers but not in never or former smokers (heterogeneity p = 0.016, 0.024, 0.021, and 0.016, respectively). We tested the clinical relevance of findings in ever smokers without asthma: 10 cigarettes/day maternal smoking increased prevalent COPD by 1.7 (95% confidence interval: 1.2–2.5) after adjustment for covariates. Maternal smoking impairs lung volume irrespective of personal smoking and appears to synergize with personal smoking to increase airflow limitation and COPD.


Click Here to Purchase Entire Article from American Journal of Respiratory and Critical Care Medicine


footer

 Home  Search  About ASH  Why Join  Comment  Email Page Contact
Contribute
Custody
Apartments


Raising Smoking as an Issue in Child Custody Disputes
Fighting Smoking in Condos and Apartments 
File Complaints Against Smoking
The Deadly Toxins in Tobacco Smoke
The Dangers of Secondhand Smoke
Govt. Rpt. on Secondhand Smoke
Tobacco Class-Action Law Suits, and How You Can Participate 
Sue-Big-Tobacco List of Anti-tobacco Lawyers
Tobacco Multistate
Settlement

Do A Survey, Win a Free Prize
Smoking Facts & Statistics
Children and Smoking

Presented as a public service by Action on Smoking and Health (ASH)
2013 H Street, N.W., Wash., DC 20006, Tel: (202) 659-4310


ASH, founded in 1968, is the national legal-action antismoking and nonsmokers' rights organization which helped ban cigarette commercials, started the modern nonsmokers' rights movement, pioneered using legal action against smoking, developed novel legal theories to protect children from tobacco smoke at home and in cars, get lower health insurance rates for nonsmokers, fought tobacco subsidies, and much much more.

ASH is entirely supported by tax-deductible contributions.
  Material on this page may be freely reproduced, distributed, and circulated,
but please credit ASH, and include ASH's web address:
http://ash.org